An innovative medtech company

WISE Srl is a Milan- and Berlin-based medical device company developing a new generation of implantable leads for neuromonitoring and neuromodulation

WISE is a medical device company with a unique technology that allows the production of stretchable and flexible electrodes on medical-grade elastic polymers

Electrodes are used as surgical instruments and implants on neural tissues to apply electrical stimuli or to record electrical activity for neuromonitoring and neuromodulation.

WISE’s electrodes are highly ergonomic, conformable, soft and thin, thus allowing great adhesion, minimal invasiveness and excellent adaptability on neural tissues, addressing major limitations of other existing technologies. They have the potential to improve the performance of neuromonitoring as well as treatment quality for patients who are already benefiting from neuromodulation.

WISEneuro® portfolio

Our WISEneuro® portfolio focuses on products for neuromonitoring and neuromodulation:

The WISEneuro® Monitoring family is being launched with the CE-marked WISE Cortical Strip for intraoperative neurophysiological monitoring during brain tumor and epilepsy surgeries.
More about the WISE Cortical Strip

The WISEneuro® Modulation family will include the Heron® lead, the first paddle lead for SCS that is expandable and can be implanted percutaneously by pain therapists and neurosurgeons.
More about the WISE Heron® lead


Our proprietary disruptive Supersonic Technology enables the production of electrodes embedded in elastic polymers, such as silicone.

These electrodes therefore are stretchable, flexible, biocompatible (medical grade) and allow effective stimulation and recording.

We can embed electronic circuits in foils as thin as a few microns, without damaging the foil itself. Our technology allows the production of electrodes with any number of contacts in a variety of shapes, density or size, ranging from the micro to the macro scale.

Our Supersonic Technology has the potential to revolutionize the way stretchable electronics is produced, potentially going beyond medical devices. This technology is applicable to a wide range of applications in numerous fields, such as brain-machine interfaces, medical implants, stretchable & wearable electronics, optics, aerospace industry, and much more.

Quality certification

WISE’s manufacturing site in Italy (Milan) is ISO13485:2016 certified for the design and development, production and sales of our cortical electrodes.